Simple Radiometric Method for Accurately Quantitating Epitope Densities of Hapten–Protein Conjugates with Sulfhydryl Linkages

[Image: see text] Control of small molecule hapten epitope densities on antigenic carrier proteins is essential for development and testing of optimal conditions for vaccines. Yet, accurate determination of epitope density can be extremely difficult to accomplish, especially with the use of small ha...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Peterson, Eric C., Hambuchen, Michael D., Tawney, Rachel L., Gunnell, Melinda G., Cowell, James L., Lay, Jackson O., Blough, Bruce E., Carroll, F. Ivy, Owens, S. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275166/
https://ncbi.nlm.nih.gov/pubmed/25426820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500456z
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