Radiolabeling of Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomography

[Image: see text] The avidin–biotin interaction permits rapid and nearly irreversible noncovalent linkage between biotinylated molecules and avidin-modified substrates. We designed a biotinylated radioligand intended for use in the detection of avidin-modified polymer nanoparticles in tissue with po...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Sirianni, Rachael W., Zheng, Ming-Qiang, Patel, Toral R., Shafbauer, Thomas, Zhou, Jiangbing, Saltzman, W. Mark, Carson, Richard E., Huang, Yiyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275164/
https://ncbi.nlm.nih.gov/pubmed/25322194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500315j
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