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Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with Positron Emission Tomography

PURPOSE: Our goal was to use Positron Emission Tomography (PET) to analyze the movement of radiolabeled agents in tissue to enable direct measurement of drug delivery to the brain. PROCEDURES: A variety of 11C- and 18F-labeled compounds were delivered directly to an agarose phantom or rat striatum....

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Detalhes bibliográficos
Main Authors: Sirianni, Rachael W., Zheng, Ming-Qiang, Saltzman, W. Mark, Huang, Yiyun, Carson, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942322/
https://ncbi.nlm.nih.gov/pubmed/23624949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-013-0636-9
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