The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

Exploiting genotyping, DNA sequencing, imputation and trans-ancestral mapping, we used Bayesian and frequentist approaches to model the IRF5–TNPO3 locus association, now implicated in two immunotherapies and seven autoimmune diseases. Specifically, in systemic lupus erythematosus (SLE), we resolved...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Kottyan, Leah C., Zoller, Erin E., Bene, Jessica, Lu, Xiaoming, Kelly, Jennifer A., Rupert, Andrew M., Lessard, Christopher J., Vaughn, Samuel E., Marion, Miranda, Weirauch, Matthew T., Namjou, Bahram, Adler, Adam, Rasmussen, Astrid, Glenn, Stuart, Montgomery, Courtney G., Hirschfield, Gideon M., Xie, Gang, Coltescu, Catalina, Amos, Chris, Li, He, Ice, John A., Nath, Swapan K., Mariette, Xavier, Bowman, Simon, Rischmueller, Maureen, Lester, Sue, Brun, Johan G., Gøransson, Lasse G., Harboe, Erna, Omdal, Roald, Cunninghame-Graham, Deborah S., Vyse, Tim, Miceli-Richard, Corinne, Brennan, Michael T., Lessard, James A., Wahren-Herlenius, Marie, Kvarnström, Marika, Illei, Gabor G., Witte, Torsten, Jonsson, Roland, Eriksson, Per, Nordmark, Gunnel, Ng, Wan-Fai, Anaya, Juan-Manuel, Rhodus, Nelson L., Segal, Barbara M., Merrill, Joan T., James, Judith A., Guthridge, Joel M., Hal Scofield, R., Alarcon-Riquelme, Marta, Bae, Sang-Cheol, Boackle, Susan A., Criswell, Lindsey A., Gilkeson, Gary, Kamen, Diane L., Jacob, Chaim O., Kimberly, Robert, Brown, Elizabeth, Edberg, Jeffrey, Alarcón, Graciela S., Reveille, John D., Vilá, Luis M., Petri, Michelle, Ramsey-Goldman, Rosalind, Freedman, Barry I., Niewold, Timothy, Stevens, Anne M., Tsao, Betty P., Ying, Jun, Mayes, Maureen D., Gorlova, Olga Y., Wakeland, Ward, Radstake, Timothy, Martin, Ezequiel, Martin, Javier, Siminovitch, Katherine, Moser Sivils, Kathy L., Gaffney, Patrick M., Langefeld, Carl D., Harley, John B., Kaufman, Kenneth M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Association Studies Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275071/
https://ncbi.nlm.nih.gov/pubmed/25205108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu455
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