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Motoneuron development influences dorsal root ganglia survival and Schwann cell development in a vertebrate model of spinal muscular atrophy

Low levels of the survival motor neuron protein (SMN) cause the disease spinal muscular atrophy. A primary characteristic of this disease is motoneuron dysfunction and paralysis. Understanding why motoneurons are affected by low levels of SMN will lend insight into this disease and to motoneuron bio...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Hao, Le Thi, Duy, Phan Q., Jontes, James D., Beattie, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275068/
https://ncbi.nlm.nih.gov/pubmed/25180019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu447
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