Neuronal T-Cell Autoreactivity Is Amplified in Overweight Children With New-Onset Insulin-Requiring Diabetes

OBJECTIVE: Disease-associated T-cell autoreactivities are seen in most type 1 diabetic patients and are thought to emerge before islet autoantibodies, but host factors that impact autoimmune elements remain uncertain. We assessed if adiposity and measures of insulin sensitivity impact T- and B-cell...

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Bibliographic Details
Published in:Diabetes Care
Main Authors: Buryk, Melissa A., Dosch, H-Michael, Libman, Ingrid, Arena, Vincent C., Huang, Yihe, Cheung, Roy K., Trucco, Massimo, Pietropaolo, Massimo, Becker, Dorothy J.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2015
Subjects:
Clinical Care/Education/Nutrition/Psychosocial Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274776/
https://ncbi.nlm.nih.gov/pubmed/25414154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc14-1861
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