Mucosal Vaccination against Serogroup B Meningococci: Induction of Bactericidal Antibodies and Cellular Immunity following Intranasal Immunization with NadA of Neisseria meningitidis and Mutants of Escherichia coli Heat-Labile Enterotoxin

Conjugated polysaccharide vaccines protect against serogroup C meningococci. However, this approach cannot be applied to serogroup B, which is still a major cause of meningitis. We evaluated the immunogenicity of three surface-exposed proteins from serogroup B Neisseria meningitidis (App, NhhA, and...

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Detalhes bibliográficos
Main Authors: Bowe, Frances, Lavelle, Ed C., McNeela, Edel A., Hale, Christine, Clare, Simon, Arico, Beatrice, Giuliani, Marzia M., Rae, Aaron, Huett, Alan, Rappuoli, Rino, Dougan, Gordon, Mills, Kingston H. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427466/
https://ncbi.nlm.nih.gov/pubmed/15213150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4052-4060.2004
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