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Interpreting 16S metagenomic data without clustering to achieve sub-OTU resolution

The standard approach to analyzing 16S tag sequence data, which relies on clustering reads by sequence similarity into Operational Taxonomic Units (OTUs), underexploits the accuracy of modern sequencing technology. We present a clustering-free approach to multi-sample Illumina data sets that can ide...

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Bibliografiska uppgifter
I publikationen:ISME J
Huvudupphovsmän: Tikhonov, Mikhail, Leach, Robert W, Wingreen, Ned S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274427/
https://ncbi.nlm.nih.gov/pubmed/25012900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2014.117
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