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Interpreting 16S metagenomic data without clustering to achieve sub-OTU resolution

The standard approach to analyzing 16S tag sequence data, which relies on clustering reads by sequence similarity into Operational Taxonomic Units (OTUs), underexploits the accuracy of modern sequencing technology. We present a clustering-free approach to multi-sample Illumina data sets that can ide...

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Detalhes bibliográficos
Publicado no:ISME J
Main Authors: Tikhonov, Mikhail, Leach, Robert W, Wingreen, Ned S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274427/
https://ncbi.nlm.nih.gov/pubmed/25012900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2014.117
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