Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid

Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is believed to play an important role in tumorigenesis. In this study, a p...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Han, Songyi, Huh, Jeongsoon, Kim, Wooseong, Jeong, Seongkeun, Min, Do Sik, Jung, Yunjin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274397/
https://ncbi.nlm.nih.gov/pubmed/25523098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.86
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