Responses of Well-Differentiated Airway Epithelial Cell Cultures from Healthy Donors and Patients with Cystic Fibrosis to Burkholderia cenocepacia Infection

Well-differentiated cultures established from airway epithelia of patients with cystic fibrosis (CF cultures) exhibited goblet cell hyperplasia, increased secretion of mucus, and higher basal levels of interleukin-8 than similarly cultured cells from healthy donors. Upon apical infection with low do...

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Bibliographic Details
Main Authors: Sajjan, Umadevi, Keshavjee, Shaf, Forstner, Janet
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC427436/
https://ncbi.nlm.nih.gov/pubmed/15213163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4188-4199.2004
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