Responses of Well-Differentiated Airway Epithelial Cell Cultures from Healthy Donors and Patients with Cystic Fibrosis to Burkholderia cenocepacia Infection

Well-differentiated cultures established from airway epithelia of patients with cystic fibrosis (CF cultures) exhibited goblet cell hyperplasia, increased secretion of mucus, and higher basal levels of interleukin-8 than similarly cultured cells from healthy donors. Upon apical infection with low do...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Sajjan, Umadevi, Keshavjee, Shaf, Forstner, Janet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15213163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.7.4188-4199.2004
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