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DEAF1 Binds Unmethylated and Variably Spaced CpG Dinucleotide Motifs
DEAF1 is a transcriptional regulator associated with autoimmune and neurological disorders and is known to bind TTCG motifs. To further ascertain preferred DEAF1 DNA ligands, we screened a random oligonucleotide library containing an “anchored” CpG motif. We identified a binding consensus that gener...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4274154/ https://ncbi.nlm.nih.gov/pubmed/25531106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115908 |
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