Regulation of NF-κB signaling by oxidized glycerophospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic endothelial cells

Exposure of endothelial cells (ECs) to agents such as oxidized glycerophospholipids (oxGPs) and cytokines, known to accumulate in atherosclerotic lesions, perturbs the expression of hundreds of genes in ECs involved in inflammatory and other biological processes. We hypothesized that microRNAs (miRN...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Romay, Milagros C., Che, Nam, Becker, Scott N., Pouldar, Delila, Hagopian, Raffi, Xiao, Xinshu, Lusis, Aldons J., Berliner, Judith A., Civelek, Mete
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274069/
https://ncbi.nlm.nih.gov/pubmed/25327529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M052670
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