Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts

BACKGROUND: Cathelicidin (LL-37 in humans and mCRAMP in mice) represents a family of endogenous antimicrobial and anti-inflammatory peptides. Cancer-associated fibroblasts can promote the proliferation of colon cancer cells and growth of colon cancer tumors. METHODS: We examined the role of cathelic...

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Опубликовано в: :Clin Exp Gastroenterol
Главные авторы: Cheng, Michelle, Ho, Samantha, Yoo, Jun Hwan, Tran, Deanna Hoang-Yen, Bakirtzi, Kyriaki, Su, Bowei, Tran, Diana Hoang-Ngoc, Kubota, Yuzu, Ichikawa, Ryan, Koon, Hon Wai
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2014
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274046/
https://ncbi.nlm.nih.gov/pubmed/25565877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S70906
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