Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production

Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been associated with inflammatory and autoimmune diseases. Soluble TLR2 (sTLR2) variants have been identified...

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Veröffentlicht in:PLoS One
Hauptverfasser: Langjahr, Patricia, Díaz-Jiménez, David, De la Fuente, Marjorie, Rubio, Estefhany, Golenbock, Douglas, Bronfman, Francisca C., Quera, Rodrigo, González, María-Julieta, Hermoso, Marcela A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273945/
https://ncbi.nlm.nih.gov/pubmed/25531754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104624
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