Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production

Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been associated with inflammatory and autoimmune diseases. Soluble TLR2 (sTLR2) variants have been identified...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Langjahr, Patricia, Díaz-Jiménez, David, De la Fuente, Marjorie, Rubio, Estefhany, Golenbock, Douglas, Bronfman, Francisca C., Quera, Rodrigo, González, María-Julieta, Hermoso, Marcela A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273945/
https://ncbi.nlm.nih.gov/pubmed/25531754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104624
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