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Optimization of pilocarpine-mediated seizure induction in immunodeficient Nod-Scid mice

Temporal lobe epilepsy (TLE) has been modeled in mice using pilocarpine induction, with variable results depending on specific strains. To allow efficient xenotransplantation for the purpose of optimizing potential cell-based therapy of human TLE, we have determined the optimal dosing strategy to pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epilepsy Res
Hauptverfasser: Leung, Amanda, Ahn, Sandra, Savvidis, George, Kim, Yeachan, Iskandar, Danielle, Luna, Maria Jose, Kim, Kwang-Soo, Cunningham, Miles, Chung, Sangmi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273671/
https://ncbi.nlm.nih.gov/pubmed/25524850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2014.10.016
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