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Subretinal infiltration of monocyte derived cells and complement misregulation in mice with AMD-like pathology
We have characterized a naturally-occurring mutation in mice that causes slow, progressive photoreceptor degeneration, white fundus flecks, and late-onset RPE atrophy. These animals predictably lose visual function as photoreceptors degenerate. Genetic studies identified a deletion in the 5′ coding...
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| Pubblicato in: | Adv Exp Med Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273561/ https://ncbi.nlm.nih.gov/pubmed/24664718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_45 |
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