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Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury

Proinflammatory mediators trigger intensive postischemic inflammatory remodeling of the blood–brain barrier (BBB) including extensive brain endothelial cell surface and junctional complex changes. Junctional adhesion molecule-A (JAM-A) is a component of the brain endothelial junctional complex with...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Sladojevic, Nikola, Stamatovic, Svetlana M., Keep, Richard F., Grailer, Jamison J., Sarma, J. Vidya, Ward, Peter A., Andjelkovic, Anuska V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273560/
https://ncbi.nlm.nih.gov/pubmed/24657919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.03.010
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