Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR) significan...

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Vydáno v:Respir Res
Hlavní autoři: Hostettler, Katrin E, Zhong, Jun, Papakonstantinou, Eleni, Karakiulakis, George, Tamm, Michael, Seidel, Petra, Sun, Qingzhu, Mandal, Jyotshna, Lardinois, Didier, Lambers, Christopher, Roth, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273482/
https://ncbi.nlm.nih.gov/pubmed/25496490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0157-3
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