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DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1
BACKGROUND: Airway wall remodelling is an important pathology of asthma. Growth factor induced airway smooth muscle cell (ASMC) proliferation is thought to be the major cause of airway wall thickening in asthma. Earlier we reported that Dimethylfumarate (DMF) inhibits platelet-derived growth factor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972257/ https://ncbi.nlm.nih.gov/pubmed/20961405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-145 |
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