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Site-specific cation release drives actin filament severing by vertebrate cofilin

Actin polymerization powers the directed motility of eukaryotic cells. Sustained motility requires rapid filament turnover and subunit recycling. The essential regulatory protein cofilin accelerates network remodeling by severing actin filaments and increasing the concentration of ends available for...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kang, Hyeran, Bradley, Michael J., Cao, Wenxiang, Zhou, Kaifeng, Grintsevich, Elena E., Michelot, Alphée, Sindelar, Charles V., Hochstrasser, Mark, De La Cruz, Enrique M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273407/
https://ncbi.nlm.nih.gov/pubmed/25468977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413397111
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