Cofilin-Linked Changes in Actin Filament Flexibility Promote Severing

The actin regulatory protein, cofilin, increases the bending and twisting elasticity of actin filaments and severs them. It has been proposed that filaments partially decorated with cofilin accumulate stress from thermally driven shape fluctuations at bare (stiff) and decorated (compliant) boundarie...

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Autori principali: McCullough, Brannon R., Grintsevich, Elena E., Chen, Christine K., Kang, Hyeran, Hutchison, Alan L., Henn, Arnon, Cao, Wenxiang, Suarez, Cristian, Martiel, Jean-Louis, Blanchoin, Laurent, Reisler, Emil, De La Cruz, Enrique M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
Soggetti:
Muscle, Motility, and Motor Protein
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127193/
https://ncbi.nlm.nih.gov/pubmed/21723825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.049
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