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Evolution-guided optimization of biosynthetic pathways
Engineering biosynthetic pathways for chemical production requires extensive optimization of the host cellular metabolic machinery. Because it is challenging to specify a priori an optimal design, metabolic engineers often need to construct and evaluate a large number of variants of the pathway. We...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273373/ https://ncbi.nlm.nih.gov/pubmed/25453111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409523111 |
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