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Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

Fluorescence of the dye 33258 Hoechst bound to chromosomes is partially quenched by the introduction of BrdU into chromosomal DNA. This finding has allowed microfluorometric detection of DNA synthesis in human metaphase chromosomes. Incorporation, shortly before cell harvest, of a pulse of thymidine...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijä: Latt, Samuel A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1973
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427244/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4128545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.12.3395
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