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Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

Fluorescence of the dye 33258 Hoechst bound to chromosomes is partially quenched by the introduction of BrdU into chromosomal DNA. This finding has allowed microfluorometric detection of DNA synthesis in human metaphase chromosomes. Incorporation, shortly before cell harvest, of a pulse of thymidine...

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Bibliografische gegevens
Hoofdauteur: Latt, Samuel A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1973
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC427244/
https://ncbi.nlm.nih.gov/pubmed/4128545
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