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Protein Flexibility in Docking and Surface Mapping

Structure-based drug design has become an essential tool for rapid lead discovery and optimization. As available structural information has increased, researchers have become increasingly aware of the importance of protein flexibility for accurate description of the native state. Typical protein–lig...

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Detalhes bibliográficos
Publicado no:Q Rev Biophys
Main Authors: Lexa, Katrina W., Carlson, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272345/
https://ncbi.nlm.nih.gov/pubmed/22569329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583512000066
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