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Protein Flexibility in Docking and Surface Mapping

Structure-based drug design has become an essential tool for rapid lead discovery and optimization. As available structural information has increased, researchers have become increasingly aware of the importance of protein flexibility for accurate description of the native state. Typical protein–lig...

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書目詳細資料
發表在:Q Rev Biophys
Main Authors: Lexa, Katrina W., Carlson, Heather A.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272345/
https://ncbi.nlm.nih.gov/pubmed/22569329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583512000066
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