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Simvastatin Reduces Burn Injury-induced Splenic Apoptosis via Down-regulation of the TNF-α/ NF-κB Pathway
OBJECTIVE: Recent studies have suggested that epidermal burn injuries are associated with inflammation and immune dysfunction. Simvastatin has been shown to possess potent anti-inflammatory properties. Thus we hypothesized that simvastatin protects against burn-induced apoptosis in spleen via its an...
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| Publicado no: | Ann Surg |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272342/ https://ncbi.nlm.nih.gov/pubmed/24950285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000000764 |
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