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Simvastatin Reduces Burn Injury-induced Splenic Apoptosis via Down-regulation of the TNF-α/ NF-κB Pathway

OBJECTIVE: Recent studies have suggested that epidermal burn injuries are associated with inflammation and immune dysfunction. Simvastatin has been shown to possess potent anti-inflammatory properties. Thus we hypothesized that simvastatin protects against burn-induced apoptosis in spleen via its an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Surg
Päätekijät: Zhao, Gaofeng, Yu, Yong-Ming, Kaneki, Masao, Bonab, Ali A., Tompkins, Ronald G., Fischman, Alan J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272342/
https://ncbi.nlm.nih.gov/pubmed/24950285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000000764
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