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Surrogacy Assessment Using Principal Stratification and a Gaussian Copula Model

In clinical trials, a surrogate outcome (S) can be measured before the outcome of interest (T) and may provide early information regarding the treatment (Z) effect on T. Many methods of surrogacy validation rely on models for the conditional distribution of T given Z and S. However, S is a post-rand...

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Publicado en:Stat Methods Med Res
Main Authors: Conlon, A.S.C., Taylor, J.M.G., Elliott, M.R.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272338/
https://ncbi.nlm.nih.gov/pubmed/24947559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280214539655
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