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The Selective Antagonism of P2X(7) and P2Y(1) Receptors Prevents Synaptic Failure and Affects Cell Proliferation Induced by Oxygen and Glucose Deprivation in Rat Dentate Gyrus

Purinergic P2X and P2Y receptors are broadly expressed on both neurons and glial cells in the central nervous system (CNS), including dentate gyrus (DG). The aim of this research was to determine the synaptic and proliferative response of the DG to severe oxygen and glucose deprivation (OGD) in acut...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Maraula, Giovanna, Lana, Daniele, Coppi, Elisabetta, Gentile, Francesca, Mello, Tommaso, Melani, Alessia, Galli, Andrea, Giovannini, Maria Grazia, Pedata, Felicita, Pugliese, Anna Maria
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272279/
https://ncbi.nlm.nih.gov/pubmed/25526634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115273
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