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Role of Guanine Nucleotides in Protein Synthesis. Elongation Factor G and Guanosine 5′-Triphosphate,3′-Diphosphate

The possible role of guanosine 5′-triphosphate,3′-diphosphate (pppGpp) in protein synthesis by Escherichia coli ribosomes and protein factors was examined. Although pppGpp could effectively substitute for GTP in reactions catalyzed by initiation factor 2 (ribosomal binding of fMet-tRNA and formation...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Hamel, Ernest, Cashel, Michael
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1973
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427210/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4594040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3250
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