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Mechanism of the in vitro breakdown of guanosine 5'-diphosphate 3'-diphosphate in Escherichia coli.

Degradation of guanosine tetraphosphate (ppGpp) involves an enzyme associated with the ribosomal fraction from spoT+ strains of Escherichia coli. Double-label experiments with pp[3h]gpp, pp[3H]Gpp, or pp[3H]Gpp as substrate strongly suggest that ppG is the degradation product and that the enzyme rel...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Heinemeyer, E A, Richter, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/212739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4180
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