Single-Cell, Genome-wide Sequencing Identifies Clonal Somatic Copy-Number Variation in the Human Brain

De novo copy-number variants (CNVs) can cause neuropsychiatric disease, but the degree to which they occur somatically, and during development, is unknown. Single-cell whole-genome sequencing (WGS) in >200 single cells, including >160 neurons from three normal and two pathological human brains...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Cai, Xuyu, Evrony, Gilad D., Lehmann, Hillel S., Elhosary, Princess C., Mehta, Bhaven K., Poduri, Annapurna, Walsh, Christopher A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272008/
https://ncbi.nlm.nih.gov/pubmed/25159146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.043
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk