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Cytogenetic Engineering In Vivo: Restoration of Biologic Complement Activity to C5-Deficient Mice by Intravenous Inoculation of Hybrid Cells

Splenic macrophages were identified as at least one source of C5 elaboration in normal mice. Hybrid cells were formed from splenic macrophages from C5-deficient mice and either kidney cells from mice with normal amounts of C5 or chicken erythrocytes. These hybrids elaborated C5 in vitro. C5-Deficien...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Levy, Nelson L., Snyderman, Ralph, Ladda, Roger L., Lieberman, Rose
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1973
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4131744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3125
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