Cytogenetic Engineering In Vivo: Restoration of Biologic Complement Activity to C5-Deficient Mice by Intravenous Inoculation of Hybrid Cells

Splenic macrophages were identified as at least one source of C5 elaboration in normal mice. Hybrid cells were formed from splenic macrophages from C5-deficient mice and either kidney cells from mice with normal amounts of C5 or chicken erythrocytes. These hybrids elaborated C5 in vitro. C5-Deficien...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Levy, Nelson L., Snyderman, Ralph, Ladda, Roger L., Lieberman, Rose
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1973
Assuntos:	Biological Sciences: Immunology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4131744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3125
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