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Epidermal Growth Factor: Receptors in Human Fibroblasts and Modulation of Action by Cholera Toxin

Epidermal growth factor (EGF) stimulates both DNA and RNA synthesis in contact-inhibited human fibroblasts. Stimulation of DNA synthesis is observed at concentrations as low as 3 pM, is half-maximal at 70 pM, and is maximal at 300 pM EGF. The action of EGF is similar to that of fetal-calf serum, but...

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Bibliografiske detaljer
Main Authors: Hollenberg, Morley D., Cuatrecasas, Pedro
Format: Artigo
Sprog:Inglês
Udgivet: 1973
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC427148/
https://ncbi.nlm.nih.gov/pubmed/4355377
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