Epidermal Growth Factor: Receptors in Human Fibroblasts and Modulation of Action by Cholera Toxin
Epidermal growth factor (EGF) stimulates both DNA and RNA synthesis in contact-inhibited human fibroblasts. Stimulation of DNA synthesis is observed at concentrations as low as 3 pM, is half-maximal at 70 pM, and is maximal at 300 pM EGF. The action of EGF is similar to that of fetal-calf serum, but...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1973
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427148/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4355377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.10.2964 |
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