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Inhibition of Arginyltransferase 1 Induces Transcriptional Activity of Myocardin-related Transcription Factor A (MRTF-A) and Promotes Directional Migration

Myocardin-related transcription factor A (MRTF-A/MAL/MKL1/BSAC) regulates the expression of serum-response factor (SRF)-dependent target genes in response to the Rho-actin signaling pathway. Overexpression or activation of MRTF-A affects shape, migration, and invasion of cells and contributes to hum...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Eisenach, Patricia A., Schikora, Franziska, Posern, Guido
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271223/
https://ncbi.nlm.nih.gov/pubmed/25381249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578674
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