Cytoskeletal Regulation of CD44 Membrane Organization and Interactions with E-selectin

Interactions of CD44 on neutrophils with E-selectin on activated endothelial cells mediate rolling under flow, a prerequisite for neutrophil arrest and migration into perivascular tissues. How CD44 functions as a rolling ligand despite its weak affinity for E-selectin is unknown. We examined the nan...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Wang, Ying, Yago, Tadayuki, Zhang, Nan, Abdisalaam, Salim, Alexandrakis, George, Rodgers, William, McEver, Rodger P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271205/
https://ncbi.nlm.nih.gov/pubmed/25359776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600767
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