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A Short Sequence Motif in the 5′ Leader of the HIV-1 Genome Modulates Extended RNA Dimer Formation and Virus Replication

The 5′ leader of the HIV-1 RNA genome encodes signals that control various steps in the replication cycle, including the dimerization initiation signal (DIS) that triggers RNA dimerization. The DIS folds a hairpin structure with a palindromic sequence in the loop that allows RNA dimerization via int...

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Vydáno v:J Biol Chem
Hlavní autoři: van Bel, Nikki, Das, Atze T., Cornelissen, Marion, Abbink, Truus E. M., Berkhout, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271197/
https://ncbi.nlm.nih.gov/pubmed/25368321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.621425
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