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Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post–transfer refinement

When microbes acquire new abilities through horizontal gene transfer, the genes and pathways must function under conditions with which they did not coevolve. If newly-acquired genes burden the host, their utility will depend on further evolutionary refinement of the recombinant strain. We used labor...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Michener, Joshua K, Camargo Neves, Aline A, Vuilleumier, Stéphane, Bringel, Françoise, Marx, Christopher J
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271186/
https://ncbi.nlm.nih.gov/pubmed/25418043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04279
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