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In Silico Identification and Pharmacological Evaluation of Novel Endocrine Disrupting Chemicals That Act via the Ligand-Binding Domain of the Estrogen Receptor α

Endocrine disrupting chemicals (EDCs) pose a significant threat to human health, society, and the environment. Many EDCs elicit their toxic effects through nuclear hormone receptors, like the estrogen receptor α (ERα). In silico models can be used to prioritize chemicals for toxicological evaluation...

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Bibliografiska uppgifter
I publikationen:Toxicol Sci
Huvudupphovsmän: McRobb, Fiona M., Kufareva, Irina, Abagyan, Ruben
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271121/
https://ncbi.nlm.nih.gov/pubmed/24928891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu114
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