Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis

Brain bioenergetic function declines in some neurodegenerative diseases, this may influence other pathologies and administering bioenergetic intermediates could have therapeutic value. To test how one intermediate, oxaloacetate (OAA) affects brain bioenergetics, insulin signaling, inflammation and n...

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Dades bibliogràfiques
Publicat a:Hum Mol Genet
Autors principals: Wilkins, Heather M., Harris, Janna L., Carl, Steven M., E, Lezi, Lu, Jianghua, Eva Selfridge, J., Roy, Nairita, Hutfles, Lewis, Koppel, Scott, Morris, Jill, Burns, Jeffrey M., Michaelis, Mary L., Michaelis, Elias K., Brooks, William M., Swerdlow, Russell H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271074/
https://ncbi.nlm.nih.gov/pubmed/25027327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu371
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