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Effect of Cholinergic Signaling on Neuronal Cell Bioenergetics

Alzheimer's disease (AD) patients have reduced brain acetylcholine and reversing this deficit yields clinical benefits. In this study we explored how increased cholinergic tone impacts cell bioenergetics, which are also perturbed in AD. We treated SHSY5Y neuroblastoma cells with carbachol, a ch...

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Détails bibliographiques
Auteurs principaux: Lu, Jianghua, Lezi, E, Roy, Nairita, Hutfles, Lewis, Selfridge, Eva, Funk, Eric, Burns, Jeffrey M., Swerdlow, Russell H.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553319/
https://ncbi.nlm.nih.gov/pubmed/23099815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-121822
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