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Effect of Cholinergic Signaling on Neuronal Cell Bioenergetics

Alzheimer's disease (AD) patients have reduced brain acetylcholine and reversing this deficit yields clinical benefits. In this study we explored how increased cholinergic tone impacts cell bioenergetics, which are also perturbed in AD. We treated SHSY5Y neuroblastoma cells with carbachol, a ch...

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Main Authors: Lu, Jianghua, Lezi, E, Roy, Nairita, Hutfles, Lewis, Selfridge, Eva, Funk, Eric, Burns, Jeffrey M., Swerdlow, Russell H.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553319/
https://ncbi.nlm.nih.gov/pubmed/23099815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-121822
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