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Effect of Cholinergic Signaling on Neuronal Cell Bioenergetics

Alzheimer's disease (AD) patients have reduced brain acetylcholine and reversing this deficit yields clinical benefits. In this study we explored how increased cholinergic tone impacts cell bioenergetics, which are also perturbed in AD. We treated SHSY5Y neuroblastoma cells with carbachol, a ch...

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Bibliografiska uppgifter
Huvudupphovsmän: Lu, Jianghua, Lezi, E, Roy, Nairita, Hutfles, Lewis, Selfridge, Eva, Funk, Eric, Burns, Jeffrey M., Swerdlow, Russell H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553319/
https://ncbi.nlm.nih.gov/pubmed/23099815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-121822
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