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Effect of Cholinergic Signaling on Neuronal Cell Bioenergetics

Alzheimer's disease (AD) patients have reduced brain acetylcholine and reversing this deficit yields clinical benefits. In this study we explored how increased cholinergic tone impacts cell bioenergetics, which are also perturbed in AD. We treated SHSY5Y neuroblastoma cells with carbachol, a ch...

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Detalhes bibliográficos
Main Authors: Lu, Jianghua, Lezi, E, Roy, Nairita, Hutfles, Lewis, Selfridge, Eva, Funk, Eric, Burns, Jeffrey M., Swerdlow, Russell H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553319/
https://ncbi.nlm.nih.gov/pubmed/23099815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-121822
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