Hypertensive Renal Injury Is Associated with Gene Variation Affecting Immune Signaling

BACKGROUND: The spontaneously hypertensive rat (SHR) strain exists in lines that contrast strongly in susceptibility to renal injury in hypertension. These inbred lines share common ancestry and only 13% of their genomes arise from different ancestors. METHODS AND RESULTS: We used next gen sequencin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circ Cardiovasc Genet
Egile Nagusiak: Braun, Michael C., Herring, Stacy M., Gokul, Nisha, Monita, Monique, Bell, Rebecca, Zhu, Yaming, Gonzalez-Garay, Manuel L., Wenderfer, Scott E., Doris, Peter A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270933/
https://ncbi.nlm.nih.gov/pubmed/25366137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.114.000533
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