Candidate Pathway-Based GWAS Identifies Novel Associations of Genomic Variants in the Complement System Associated with Coronary Artery Disease

BACKGROUND: Genomic variants identified by genome-wide association studies (GWAS) explain <20% of heritability of coronary artery disease (CAD), thus many risk variants remain missing for CAD. Identification of new variants may unravel new biological pathways and genetic mechanisms for CAD. To id...

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Publicat a:Circ Cardiovasc Genet
Autors principals: Xu, Chengqi, Yang, Qin, Xiong, Hongbo, Wang, Longfei, Cai, Jianping, Wang, Fan, Li, Sisi, Chen, Jing, Wang, Chuchu, Wang, Dan, Xiong, Xin, Wang, Pengyun, Zhao, Yuanyuan, Wang, Xiaojing, Huang, Yufeng, Chen, Shanshan, Yin, Dan, Li, Xiuchun, Liu, Ying, Liu, Jinqiu, Wang, Jingjing, Li, Hui, Ke, Tie, Ren, Xiang, Wu, Yanxia, Wu, Gang, Wan, Jing, Zhang, Rongfeng, Wu, Tangchun, Wang, Junhan, Xia, Yunlong, Yang, Yanzong, Cheng, Xiang, Liao, Yuhua, Chen, Qiuyun, Zhou, Yanhong, He, Qing, Tu, Xin, Wang, Qing K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270888/
https://ncbi.nlm.nih.gov/pubmed/25249547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.114.000738
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